The University of Chicago's Research Computing Center measured NVIDIA's B300 running a 70B Llama-3 model at 24% to 27% lower throughput than the previous-generation B200.
(preprint, arXiv 2610.41919)

A new GPU generation isn't guaranteed to beat its predecessor on every workload, though only this one team has measured it and software versions may sway the result. Mohsen Zand, Trung Dac Nguyen and H. Birali Runesha published on October 30, comparing the two GPUs on two independent eight-GPU clusters (arXiv 2610.41919). The authors also found that two B300 servers of the same model, each running a different development build of vLLM, differed by 2.1 times in time to first token, the wait from sending a request to seeing the first output token. vLLM is widely used inference software. Outside the 70B language model, the gaps are larger. The B200 is 16 times as fast as the B300 on double-precision computation in the materials simulation code Quantum ESPRESSO. It is 8 times as fast on 3D vision transformer training and up to 5.6 times as fast on convolutional image inference. On the workloads where it trails, the authors observed the B300 drawing only 36% to 53% of its 1,100-watt power limit. On the image model ViT-Large, where the B300 wins, both GPUs reach 95% to 97% of their power limits. The abstract doesn't attribute each shortfall to a specific cause. How we checked →
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SecondSource (2026). "The University of Chicago's Research Computing Center measured NVIDIA's B300 running a 70B Llama-3 model at 24% to 27% lower throughput than the previous-generation B200.." https://secondsource.io/en/research/2026-11-02-1/. Accessed access date.